Organic Chemistry

MilesDown: Organic Chemistry

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When ____ react with a ketone , a/an ketal is formed

Nitrogen and nitrogen derivatives react with carbonyls to form ____

Nitrogen and nitrogen derivatives react with ____ to form imines

Imines can tautomerize to form ____.

Imines can t____o form enamines.

____ can tautomerize to form enamines.

Hydrogen cyanide reacts with carbonyls to form ____

____ reacts with carbonyls to form cyanohydrins

Hydrogen cyanide reacts with ____ to form cyanohydrins

Identify the α-carbon ____

Identify the α-hydrogens

A/an ____ is formed when an α-hydrogen in the molecule of an aldehyde or a ketone is removed.

A/an enolate anion is formed when ____ in the molecule of an aldehyde or a ketone is removed.

A/an enolate anion is formed when an α-hydrogen in the molecule of ____ is removed.

Aldehydes are usually ____ reactive toward nucleophilic substitutions than ketones because of both steric and electronic effects.

Aldehydes are usually more reactive toward nucleophilic substitutions than ketones because of ____.

____ because of both steric and electronic effects.

This is the ____ form of acetone.

This is the keto form of acetone.

This is the keto form of ____.

The term " enol " comes from the fact that it is a/an ____

The term "____" comes from the fact that it is a/an alkene that is also a/an alcohol

____ refers to a chemical equilibrium between a keto form and an enol

Keto-enol tautomerization refers to a ____ between a keto form and an enol

Keto form is much ____ common than enol form.

____ form.

In a Michael addition reaction, a/an ____, creating a bond.

In a ____ reaction, a/an enolate attacks a/an α,β-unsaturated carbonyl, creating a bond.

Removal of a proton from the less substituted (and less hindered) α-carbon gives the ____ enolate.

Removal of a proton from the ____ hindered) α-carbon gives the kinetic enolate.

Removal of a ____ from the less substituted (and less hindered) α-carbon gives the kinetic enolate.

Removal of a proton from the more substituted (and more hindered) α-carbon gives the ____ enolate.

Removal of a proton from the ____ hindered) α-carbon gives the thermodynamic enolate.

An aldol is a/an ____.

____ is a/an aldehyde plus a/an alcohol.

Aldol addition is a powerful way to create a ____ bond.

Aldol ____ is a powerful way to create a carbon-carbon bond.

An aldol condensation reaction starts with a/an ____.

____ reaction starts with a/an aldol addition to create a/an aldol.

An aldol nucleophile is the ____ formed from the deprotonation of the α-carbon.

An aldol nucleophile is the enolate formed from ____.

An aldol ____ is the enolate formed from the deprotonation of the α-carbon.

An aldol electrophile is a/an ____.

An aldol ____ is a/an aldehyde or ketone.

A/an ____ is the reverse of an aldol reaction.

____ functional groups contain a carbonyl and a hydroxyl group connected to the same carbon.

Carboxylic acids use the suffix ____.

____ use the suffix – oic acid .

Carboxylic acids have a high boiling point due to ____

Carboxylic acids have a high ____ due to hydrogen bonding

The acidity of a carboxylic acid can be enhanced by substituents that are electron-____.

The ____ of a carboxylic acid can be enhanced by substituents that are electron-withdrawing.

The acidity of a carboxylic acid can be ____ by substituents that are electron-withdrawing.

The acidity of a carboxylic acid can be decreased by substituents that are electron-____

The acidity of a carboxylic acid can be ____ by substituents that are electron-donating

Identify the acidic proton ____

Identify the most acidic proton

Carboxylic acids can be made by the o____f 1° alcohols or aldehydes .

Carboxylic acids can be made by the oxidation of ____.

____ can be made by the oxidation of 1° alcohols or aldehydes .

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