83 cards
The ____ product is favored in reactions that are slow, reversible, at higher temperatures, and with a weaker, smaller base.
Enamines are tautomers of ____.
____ are tautomers of imines.
An i____s a compound that contains a C=N bond.
An imine is a compound that contains a ____ bond.
____ form is thermodynamically favored over the enamine form.
Imine form is thermodynamically favored over the ____ form.
In ____, it’s a nucleophilic addition reaction, with the carbonyl-containing compound acting as both a nucleophile and an electrophile.
In aldol condensations, it’s a ____ reaction, with the carbonyl-containing compound acting as both a nucleophile and an electrophile.
Aldol Condensation: Formation of Aldol Reaction Step #1: ____. Step #2: Nucleophilic attack of the enolate on an electrophilic carbonyl in…
Aldol Condensation: Formation of Aldol Reaction Step #1: The base removes a proton on the α carbon to form a resonance-stabilized enolate.…
Aldol Condensation: Formation of Aldol Reaction Step #1: The base removes a proton on the α carbon to form a resonance-stabilized enolate.…
Aldol condensations are most useful if ____.
Aldol Condensation: Dehydration of Aldol Step #1: The base removes a proton on the α carbon to form a resonance-stabilized enolate. Step #2…
Aldol Condensation: Dehydration of Aldol Step #1: ____. Step #2: – OH is eliminated as the electron pair of the enolate forms the new π bon…
Aldol Condensation two main steps are a____.
With a ____ temperatures, dehydration in aldol condensation occurs by an E1 or E2 mechanism.
With a strong base and high temperatures, dehydration in aldol condensation occurs by ____ mechanism.
If using multiple types of aldehydes and ketones are present in aldol reaction and you want to prevent a mixture of products you can use a…
Reverse of aldol condensation reaction is re____action.
To push the reaction in a retro-aldol direction, ____ is applied.
The retro-aldol reaction is useful for breaking bonds between ____.
The re____action is useful for breaking bonds between the α -and β -carbons of a carbonyl.