General Chemistry

1EK: General Chemistry

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____ of a oxygen containing compound involves the nucleophilic addition of an oxygen to a carbon.

Oxidation of a oxygen containing compound involves the nucleophilic addition of ____ to a carbon.

Oxidation is an increase in bonds to o____ bonds.

____ is an increase in bonds to oxygen or halogen, loss of C-H bonds.

____ is an increase in bonds to hydrogen or R- groups, loss of bonds to oxygen or halogen.

Reduction is an increase in bonds to ____.

Oxygen and halogens withdraw electron density to/from carbon, leaving it ____.

Oxygen and halogens ____ electron density to/from carbon, leaving it oxidized.

Hydrogens and R- groups ____ electron density to/from carbon, leaving it reduced.

Hydrogens and R- groups donate electron density to/from carbon, leaving it ____.

Alcohols can be converted to alkenes through ____ reaction.

Alcohols can be converted to ____ through dehydration, an elimination reaction.

Secondary alcohols oxidize to ____.

____ alcohols oxidize to ketones.

Primary alcohols oxidize to ____.

____ alcohols oxidize to aldehydes.

Aldehydes oxidize to ____.

Generally speaking, oxidizing agents will have several ____ atoms.

When hydrogen is bonded with anything including or to the right of carbon, hydrogen is ____.

When hydrogen is bonded with anything including and to the left of boron, hydrogen is the ____ charge.

Most reduction reactions occur by ____ attacking a carbonyl carbon.

Most re____actions occur by hydrides attacking a carbonyl carbon.

____ of LiAlH 4 (or LAH) can be used to reduce carboxylic acids and their derivatives to alcohols.

Two equivalents of ____ can be used to reduce carboxylic acids and their derivatives to alcohols.

____ can only reduce ketones and aldehydes, not carboxylic acids or esters.

____ ions are common oxidizing agents that can oxidize alcohols to carboxylic acids.

Permanganate (MnO 4 2- ), chromate (Cro 4 2- ), and dichromate (Cr 2 O 7 2- ) ions are common oxidizing agents that can oxidize ____.

____ will oxidize primary alcohols to aldehdyes and secondary alcohols to ketones.

PCC will oxidize ____.

Oxidation of a ____ is called decarboxylation.

Oxidation of a carboxylic acid to carbon dioxide gas is called ____.

The activation energy is lower for decarboxylation when the β-carbon is a ____ because either the anion intermediate is resonance stabilize…

The activation energy is lower for decarboxylation when the β-carbon is a carbonyl because either ____.

In aldol condensation, a ____.

In ____, a carbonyl nucleophile attacks another carbonyl.

The aldol condensation is possible because ____ can act as a nucleophile.

Aldol condensation occurs when one ____.

Base-Catalyzed Aldol Condensation: Aldol Addition Step #1 : The base removes an α-hydrogen, leaving an enolate ion. Step #2 : The enolate i…

Base-Catalyzed Aldol Condensation: Aldol Addition Step #1 : The base removes an α-hydrogen, leaving an enolate ion. Step #2 : The enolate i…

Base-Catalyzed Aldol Condensation: Aldol Addition Step #1 : The base removes an α-hydrogen, leaving an enolate ion. Step #2 : ____. Step #3…

Base-Catalyzed Aldol Condensation: Aldol Addition Step #1 : ____. Step #2 : The enolate ion then acts as a nucleophile, att~cking the carbo…

The reverse of aldol condensation is a re____action.

____ reaction is what splits the ATP activated glucose in half.

Pro Tip : Remember, when the molecules look complicated, find ____.

Carbohydrates, amino acids, nucleotides and lipids are linked in chains through a ____ reaction.

The formation of bonds between macromolecules is called ____.

Carbohydrates are carbon chains with ____in form.

____ are carbon chains with an alcohol on each carbon except for one, which has either an aldehyde or ketone attached in straight chain for…

A ring is formed when ____ in a nucleophilic addition reaction and forming a hemiacetal.

A ring is formed when an alcohol group on a chiral carbon far from the carbonyl acts as a nucleophile, attacking the carbonyl in a ____.

In aqueous solution, carbohydrates exist predominantly in ____ form.

Monosaccharides can also undergo i____ reactions with other monosaccharides to form acetals.

Monosaccharides can also undergo intermolecular nucleophilic substitution reactions with other monosaccharides to form ____.

When carbohydrates contain ____, they are called aldoses.

When carbohydrates contain aldehydes, they are called ____.

When carbohydrates contain ketones, they are called ____.

When carbohydrates contain ____, they are called ketoses.

Carbohydrates can also be named for the number of carbons they possess: triose, ____, and so on.

Carbohydrates can be classified based on stereochemistry and are labeled ____.

In carbohydrate stereochemistry, number all of the carbons in a Fisher projection, with number 1 being ____.

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