Biochemistry

MilesDown: Biochemistry

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A Michaelis-Menten curve is ____.

____ is the substrate concentration that gives you a reaction rate that is halfway to V max

K m is the ____ that gives you a reaction rate that is halfway to V max

K m is the substrate concentration that gives you ____

____ is the maximum rate at which an enzyme can catalyze a reaction.

V max is the ____ at which an enzyme can catalyze a reaction.

V max is the maximum rate at which ____

The Michaelis–Menten equation is:

The ____ equation is:

Cooperative enzymes display a ____ curve.

____ enzymes display a sigmoidal curve.

____ is when the binding of the first molecule of B to A changes the binding affinity of the second B molecule, making it more or less like…

Cooperative binding is when ____.

The ____ is the site of catalysis .

The active site is the site of ____

The ____ states that the enzyme and substrate are exactly complementary and fit together like a key into a lock.

The ____ states that the enzyme and substrate undergo conformational changes in order to interact fully.

A/an ____ is a metal cation that is required by some enzymes.

A/an cofactor is a ____ that is required by some enzymes.

A/an ____ is an organic molecule that is required by some enzymes.

A/an coenzyme (type of cofactor) is ____ that is required by some enzymes.

____ of an enzyme is when an enzyme is inhibited by high levels of a product from later in the same pathway .

Feedback inhibition of an enzyme is when an enzyme is inhibited by ____ .

A/an ____ binds at the active site and thus prevents the substrate from binding.

A/an competitive inhibitor binds at the ____.

A/an ____ binds only with the enzyme-substrate complex .

A/an uncompetitive inhibitor binds ____ .

A/an ____ binds at the allosteric site , away from the active site.

A/an noncompetitive inhibitor binds at the ____.

In competitive inhibition : V max : ____.

In ____ inhibition : V max : has no change. K m : goes up.

In uncompetitive inhibition : V max : ____.

In ____ inhibition : V max : goes down. K m : goes down.

In noncompetitive inhibition : V max : ____.

In ____ inhibition : V max : goes down. K m : has no change.

Lineweaver-Burk Plot : X-intercept = ____.

This graph shows the activity of a/an ____.

This graph shows the activity of a/an ____.

This graph shows the activity of a/an ____.

Lineweaver-Burk plots are described as double reciprocal plots because the X -intercept is ____; both of them reciprocals.

Lineweaver-Burk plots are described as ____.

Lineweaver-Burk plots are described as double reciprocal plots because the ____ -intercept is 1/V max ; both of them reciprocals.

An irreversible inhibitor is any inhibitor that ____e site of some enzyme, thus eliminating its activity.

____ inhibitor is any inhibitor that covalently binds to the active site of some enzyme, thus eliminating its activity.

____ is an irreversible form of enzyme inhibition that occurs when an enzyme binds a substrate analog and forms an irreversible complex .

Suicide inhibition is ____.

A/an ____ binds at the allosteric site and induces a change in the conformation of the enzyme so the substrate can no longer bind to the ac…

A/an allosteric effector binds at the ____ .

A/an ____ is an allosteric regulator that is also the substrate .

A/an homotropic effector is ____ .

A/an ____ is an allosteric regulator molecule that is different from the substrate .

A/an heterotropic effector is ____ .

____ is the chemical addition of a phosphoryl group (PO 3 - ) to an organic molecule.

Phosphorylation is the chemical addition of a ____ to an organic molecule.

____ is the chemical addition of a carbohydrate .

Glycosylation is the chemical addition of a ____.

____ are precursors to an enzyme .

Zymogens are ____ .

The Michaelis-Menten reaction scheme is:

____ compose the cytoskeleton , anchoring proteins , and much of the extracellular matrix .

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