What properties indicate that energy released by a phosphate or pyrophosphate cleavage is quite high?
Answer:
→ Adjacent phosphate groups on a nucleotide triphosphate experience a large amount of repulsion because they are negatively charged.
→ The ability of phosphate to stabilize up to three negative charges by resonance.
Note: For the first reason given up above, maintaining structure while such a great force of repulsion is occurring requires a lot of energy!