Organic Chemistry · Chapter 10: Nitrogen & Phosphorous Compounds

Question

The last step of Strecker synthesis can be performed in a____.

Answer

The last step of Strecker synthesis can be performed in aqueous acid and can be accelerated by the use of heat.
The last step of Strecker synthesis can be performed in aqueous acid and can be accelerated by the use of heat.
Note ↑: The carbonyl carbon of an amide is sp2 hybridized and has trigonal planar geometry. A second resonance structure can be drawn that delocalizes the nonbonded electron pair on the N atom. Amides are more resonance stabilized than other acyl compounds, so the resonance structure having the C=N makes a significant contribution to the hybrid.

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