Biochemistry

Chapter 7: RNA & the Genetic Code

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The central dogma states that ____.

The central dogma states that DNA is t____ to protein.

The ____ states that DNA is transcribed to RNA, which is translated to protein.

A ____ code allows multiple codons to encode for the same amino acid.

A degenerate code allows ____ codons to encode for the same amino acid.

Initiation codon: ____.

____ codon: AUG.

____ codons: UAA, UGA, UAG.

Termination codons: ____.

____ allows mutations to occur in the genetic code without effects in the protein.

Messenger RNA is synthesized in the ____′ direction.

The ____ translates the mRNA in the 5′ → 3′ direction.

The ribosome translates the mRNA in the ____′ direction.

The ribosome synthesizes the protein from the ____ terminus.

There are three main types of RNA found in cells: ____.

____ carries the information specifying the amino acid sequence of the protein to the ribosome.

Messenger RNA (mRNA) carries the information specifying the ____ to the ribosome.

Messenger RNA (mRNA) carries the information specifying the amino acid sequence of the protein to the ____.

mRNA is transcribed from ____ by RNA polymerase enzymes in the nucleus of cells.

mRNA is transcribed from template DNA strands by ____ enzymes in the nucleus of cells.

mRNA is transcribed from template DNA strands by RNA polymerase enzymes in the ____ of cells.

mRNA may undergo a host of p____rior to its release from the nucleus.

mRNA may undergo a host of posttranscriptional modifications prior to its release from the ____.

In ____, mRNA is monocistronic .

In eukaryotes, mRNA is ____ .

In ____, mRNA is polycistronic.

In prokaryotes, mRNA is ____.

____ mRNA tells us that each mRNA molecule translates into only one protein product.

____) is responsible for converting the language of nucleic acids to the language of amino acids and peptides.

Transfer RNA (tRNA) is responsible for converting the language of ____.

Each tRNA molecule contains a folded strand of RNA that includes a three-nucleotide ____.

Each tRNA molecule contains a ____ strand of RNA that includes a three-nucleotide anticodon.

Activated amino acid or charged tRNA is produced by ____.

Mature tRNA is found in the ____.

Each type of amino acid is activated by a different ____.

Amino acid activation requires two high energy bonds from ____.

The aminoacyl-tRNA synthetase transfers the activated amino acid to the ____′ end of the correct tRNA.

The ____ transfers the activated amino acid to the 3′ end of the correct tRNA.

The aminoacyl-tRNA synthetase transfers the ____ to the 3′ end of the correct tRNA.

Each tRNA has a ____ nucleotide sequence where the amino acid binds.

The ____ bond will be used to supply the energy needed to create a peptide bond during translation.

Ribosomal RNA (rRNA) is synthesized in the ____.

____ is synthesized in the nucleolus.

Many rRNA molecules function as ____ .

Ribozymes are enzymes made of ____ molecules instead of peptides.

____ helps catalyze the formation of peptide bonds.

rRNA helps catalyze the formation of ____ bonds.

During translation, the ____ on a transfer RNA (tRNA).

During translation, the codon of the ____.

During ____, the codon of the mRNA is recognized by a complementary anticodon on a transfer RNA (tRNA).

Every preprocessed eukaryotic protein starts with the exact same amino acid: ____.

If a mutation occurs and it affects one of the nucleotides in a codon, it is known as a ____.

____ mutations that produce a premature stop codon.

Nonsense mutations that produce ____.

____ mutations that produce a codon that codes for a different amino acid.

Missense mutations that produce ____.

____ mutations with no effect on protein synthesis.

____ mutations result from nucleotide addition or deletion, and change the reading frame of subsequent codons.

Frameshift mutations result from ____, and change the reading frame of subsequent codons.

Frameshift mutations result from nucleotide addition or deletion, and change ____.

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