Biochemistry

Chapter 6: DNA & Biotechnology

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____ is a method of curing genetic deficiencies by introducing a functional gene with a viral vector.

Gene therapy is a method of curing genetic deficiencies by ____.

____ are created by integrating a gene of interest into the germ line or embryonic stem cells of a developing mouse.

Transgenic mice are created by ____.

Organisms that contain cells from two different lineages are called ____ .

Transgenic mice can be mated to select for the ____.

____ mice are created by deleting a gene of interest.

Knockout mice are created by ____.

____ excision repair corrects lesions that are large enough to distort the double helix.

Nucleotide excision repair corrects lesions that are ____ enough to distort the double helix.

____ excision repair corrects lesions that are not large enough to distort the double helix.

Base excision repair corrects lesions that are ____ enough to distort the double helix.

The ____ strand is barely methylated at all.

Oncogenes are like ____.

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