Organic Chemistry · Chapter 8: Carboxylic Acids

Question

Since in decarboxylation reaction, both the electrophile and nucleophile are in the same molecule, the reaction proceeds through a ____ in its transition state.

Answer

Since in decarboxylation reaction, both the electrophile and nucleophile are in the same molecule, the reaction proceeds through a six-membered ring in its transition state.
Since in decarboxylation reaction, both the electrophile and nucleophile are in the same molecule, the reaction proceed…
Note ↓: Decarboxylation occurs readily whenever a carboxy group (COOH) is bonded to the α carbon of another carbonyl group. For example, β-keto acids also readily lose CO2 on heating to form ketones.

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