Organic Chemistry · Chapter 4: Analyzing Organic Reactions

Question

Nucleophilic attack can occur when leaving group is just as reactive as the nucleophile. ____

Answer

Nucleophilic attack can occur when leaving group is just as reactive as the nucleophile. False
Nucleophilic attack can occur when leaving group is just as reactive as the nucleophile. False
Note: Just like acid–base reactions, nucleophilic attack will only occur if the reactants are more reactive than the products. Thus, the nucleophile must be more reactive than the leaving group.
Note: We can’t use nonpolar solvents in these nucleophile–electrophile reactions because our reactants are polar—they wouldn’t dissolve!

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