Biology

Chapter 5: The Endocrine System

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Endocrine signaling involves the secretion of hormones ____

Endocrine signaling involves the secretion of ____ directly into the bloodstream.

Hormones bind to target receptors and ____

____ hormones are composed of amino acids.

Peptide hormones are composed of ____.

____ are signaling molecules that are secreted directly into the bloodstream to distant target tissues.

At target tissues, hormones bind to receptors, inducing a change in ____.

Hormones can be subdivided into the following categories: ____.

____ hormones are made up of amino acids.

Peptide hormones are made up of ____.

____ hormones are all derived from larger precursor polypeptides that are cleaved during posttranslational modification.

Peptide hormones are all derived from larger precursor polypeptides that are cleaved during ____.

After peptide hormones are cleaved, these smaller units are transported to the ____ for further modifications that activate the hormones an…

After peptide hormones are cleaved, these smaller units are transported to the Golgi apparatus for further modifications that ____

Peptide hormones are ____.

Peptide hormones cannot pass through plasma membranes. ____

The peptide hormone is considered the ____.

The connection between the hormone at the surface and the effect brought about by second messengers within the cell is known as a ____.

At each step of the signaling cascade, there is the possibility of ____.

In G protein-coupled receptors, the binding of a peptide hormone triggers the receptor to either activate or inhibit an enzyme called ____.

In ____ receptors, the binding of a peptide hormone triggers the receptor to either activate or inhibit an enzyme called adenylate cyclase.

Activation or inhibiting of adenylate cyclase can raise or lower the levels of ____ accordingly. .

Activation or inhibiting of ____ can raise or lower the levels of cAMP accordingly. .

The effects of peptide hormones are usually rapid but short-lived because ____.

Peptides are generally ____-soluble.

____ hormones are derived from cholesterol.

Steroid hormones are derived from ____.

Steroid hormones are produced primarily by ____.

Steroid hormones are derived from ____ molecules.

Steroid hormones can cross the cell membrane. ____

Steroid hormone receptors are usually ____

Upon binding to the receptor, steroid hormone–receptor complexes undergo ____.

One common form of conformational change steroid homrone-receptor complexes undergo is ____, aka pairing of two receptor–hormone complexes.

One common form of conformational change steroid homrone-receptor complexes undergo is dimerization, aka ____.

The effects of steroid hormones are faster and longer-lived than peptide hormones. ____

Steroid hormones are ____-soluble.

Steroid hormones are ____

____ hormones are derived from one or two amino acids.

Thyroid hormones are made from ____ modified by the addition of several iodine atoms.

Thyroid hormones are made from tyrosine modified by the addition of several ____ atoms.

Most important amino acid-derivative hormones we need to know are ____.

Out of the different amino acid-derivative hormones, the ____ bind to G protein–coupled receptors.

Out of the different amino acid-derivative hormones, the catecholamines (epinephrine and norepinephrine) bind to ____.

Out of the different amino acid-derivative hormones, the thyroid hormones bind to ____.

Out of the different amino acid-derivative hormones, the ____ bind to intracellular receptors.

____ hormones are secreted and then act directly on a target tissue.

____ hormones require an intermediary to act.

Tropic hormones require ____ to act.

Tropic hormones usually originate in the ____.

The ____ are all endocrine glands.

There are collections of cells within organs, such as the ____, that serve important endocrine roles.

____ is the bridge between the nervous and endocrine systems.

The hypothalamus controls the pituitary through ____ release of hormones into a portal system that directly connects the two organs.

The release of hormones by the hypothalamus is regulated by ____.

The hypothalamus secretes compounds into the ____ .

____ is a blood vessel system that directly connects the hypothalamus with the anterior pituitary.

Hypophyseal portal system is a blood vessel system that directly connects the hypothalamus with the ____.

____ → follicle-stimulating hormone (FSH) and luteinizing hormone (LH).

Gonadotropin-releasing hormone (GnRH) → ____.

____ → growth hormone (GH).

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