Question
Of all the enzymes the MCAT is most likely to test you on, the rate-limiting enzymes for each process are at the top of the list:
- Glycolysis: phosphofructokinase-1.
- Fermentation: ____.
- Glycogenesis: glycogen synthase.
- Glycogenolysis: glycogen phosphorylase.
- Gluconeogenesis: fructose-1,6-bisphosphatase.
- Pentose Phosphate Pathway: glucose-6-phosphate dehydrogenase.
Answer
Of all the enzymes the MCAT is most likely to test you on, the rate-limiting enzymes for each process are at the top of the list:
- Glycolysis: phosphofructokinase-1.
- Fermentation: lactate dehydrogenase.
- Glycogenesis: glycogen synthase.
- Glycogenolysis: glycogen phosphorylase.
- Gluconeogenesis: fructose-1,6-bisphosphatase.
- Pentose Phosphate Pathway: glucose-6-phosphate dehydrogenase.
Metabolic Pathways Interactive Diagram
Red Boxes: Rate-Limiting Enzymes!
Metabolic Pathways Interactive Diagram
Red Boxes: Rate-Limiting Enzymes!
Real World: Because glycolysis is necessary in every cell of the body, there are no known diseases caused by the complete absence of any enzyme in glycolysis; in other words, being unable to carry out glycolysis is incompatible with life. Partial enzyme defects are also rare, but include pyruvate kinase deficiency.
Real World: Because glycolysis is necessary in every cell of the body, there are no known diseases caused by the complete absence of any enzyme in glycolysis; in other words, being unable to carry out glycolysis is incompatible with life. Partial enzyme defects are also rare, but include pyruvate kinase deficiency.
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