Question
Hexokinase is widely distributed in tissues and is inhibited by its product, ____.
Answer
Hexokinase is widely distributed in tissues and is inhibited by its product, glucose 6-phosphate.
Note: Yes, this is from First Aid Step 1 used for the USMLE Step 1. The biochemistry doesn't change when going from MCAT to Medical School!
Real World: Because glycolysis is necessary in every cell of the body, there are no known diseases caused by the complete absence of any enzyme in glycolysis; in other words, being unable to carry out glycolysis is incompatible with life. Partial enzyme defects are also rare, but include pyruvate kinase deficiency.
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Glucose entry into most cells is driven by ____.
Normal glucose concentration in peripheral blood is ____ mM.
There are four glucose transporters, called ____.
Sodium-Dependent Glucose Transporters are called ____.
GLUT 2 is a ____-affinity transporter in hepatocytes and pancreatic cells.
GLUT 2 is a low-affinity transporter in ____ cells.